Antisense Drug Technology

Despite great advances in pharmaceutical technology and understanding, the process of converting the technology to commercially viable new medicines has encountered several setbacks. Providing detailed solutions to these complex problems, this book focuses on the technology of second generation antisense drugs. Edited once again by one of the most influential biotechnology authorities, the second edition continues to offer answers to challenging questions while looking ahead to the future of antisense drugs. The book covers the fundamentals of oligonucleotide-based therapeutics and hybridization-based drugs as well as therapeutic applications for cardiovascular purposes, metabolic diseases, cancer, and neurological disorders.